2024
(145) R. Kirchhoff, N. Kampschulte, C. Rothweiler, N. Rohwer, K.H. Weylandt, N. H. Schebb (2024) Ex vivo DHA supplementation suppresses prostaglandin E2 formation in primary human macrophages. Mol Nutr Food Res, doi: 10.1002/mnfr.202400716 fulltext
(144) M. Palmer, R. Kirchhoff, C. Bürger, Y. Benatzy, N. H. Schebb, B. Brüne (2024) RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signaling. Cell Death & Disease accepted for publication.
(143) N. Kampschulte, R. Kirchhoff, A. Löwen, N. H. Schebb (2024) Deducing formation routes of oxylipins by quantitative multiple heart-cutting achiral-chiral 2D-LC-MS. J Lipid Res, doi: 10.1016/j.jlr.2024.100694 fulltext
(142) L. Carpanedo, K. M. Rund, L. M. Wende, N. Kampschulte, N. H. Schebb (2024) LC-HRMS analysis of phospholipids bearing oxylipins. Anal Chim Acta, doi: 10.1016/j.aca.2024.343139 fulltext
(141) H. M.-L. Schmieta, T. Greupner, I. Schneider, S. Wrobel, V. Christa, L. Kutzner, A. Hahn, W. S. Harris, N. H. Schebb, J. P. Schuchardt (2024) Plasma levels of EPA and DHA after ingestion of a single dose of EPA and DHA ethyl esters. Lipids, doi: 10.1002/lipd.12417 abstract
(140) L. M. Lindenbeck, S. Dahlhaus, L. M. Wende, B. B. Beele, M. Frauscher, N. H. Schebb, C. W. Lehmann, J. Bornhorst, A. Slabon, B. V. M. Rodriguesa (2024) Breaking down Lignin in Gamma-Valerolactone: Advances into a Bioelectrorefinery. Green Chem Lett Rev, doi: 10.1080/17518253.2024.2390867 fulltext
(139) M. Wiebel, K. Bensberg, L. Wende, R. Grandrath, K. Plitzko, C. Bohrmann-Linde, S. Kirsch, Stefan, N.H. Schebb, (2024) Efficient and simple extraction protocol for triterpenic acids from apples. J Chem Educ, doi: 10.1021/acs.jchemed.3c01328 fulltext
(138) Y. Benatzy, M. A. Palmer, D. Lütjohann, R.-I. Ohno, N. Kampschulte, N. H. Schebb, D. C. Fuhrmann, R. G. Snodgrass, B. Brüne (2024) ALOX15B controls macrophage cholesterol homeostasis via lipid perosidation. ERK1/2 and SREBP2. Redox Biol, 72: 103149, doi: 10.1016/j.redox.2024.103149 fulltext
(137) R.-I. Ohno, M. Mainka, R. Kirchhoff, N. M. Hartung, , N. H. Schebb (2024) Sterol derivatives specifically increase anti-inflammatory oxylipin formation in M2-like macrophages by LXR-mediated induction of 15-LOX. Molecules, 29 (8), 1745, doi: 10.3390/molecules29081745 fulltext
(136) U. Seidel, K. Eberhardt, M. Wiebel, K. Lüersen, I. Ipharraguerre, F. A. Haegele, P. Winterhalter, A. Bosy-Westphal, N. H. Schebb, G. Rimbach (2024) Stearidonic acid improves eicosapentaenoic acid status: studies in humans and cultured hepatocytes. Front Nutr, 11, doi: 10.3389/fnut.2024.1359958 fulltext
(135) C. Wang, A. Kaufmann, N. Kampschulte, U. Elbelt, U. Kassner, E. Steinhagen-Thiessen, A. Pietzner, C. Schmöcker. P. M. Moriarty, D. Datta, T. Sanpietro, N. H. Schebb, K.-H. Weylandt, N. Rohwer (2024) Changing from lipoprotein apheresis to evolocumab treatment lowers circulating levels of arachidonic acid and oxylipins. Atherosclerosis Plus, 55, 55–62, doi: 10.1016/j.athplu.2024.01.005. fulltext
(134) K. M. Rund, L. Carpanedo, R. Lauterbach, T. Wermund, A. West, L. M. Wende, P. Calder, N. H. Schebb (2024) LC-ESI-HRMS - lipidomics of phospholipids – Characterization of extraction, chromatography and detection parameters. Anal BioanalChem 416, 925-944, doi: 10.1007/s00216-023-05080-0. fulltext
(133) L. Lindenbeck, V. Barra, S. Dahlhaus, L. Wende, B. Beele, N. H. Schebb, B. Rodrigues, A. Slabon (2024) Organic Chemicals from Wood: Selective Depolymerization and Dearomatization of Lignin via Aqueous Electrocatalysis. ChemSusChem, doi: 10.1002/cssc.202301617. fulltext
(132) E. Koch, A. Löwen, N. H. Schebb (2024) Do meals contain a relevant amount of oxylipins? LC-MS-based analysis of oxidized fatty acids in food. Food Chem, 438, 137941, doi: 10.1016/j.foodchem.2023.137941. abstract
2023
(131) V. B. O’Donnell, N. H. Schebb, G. L. Milne, M. P. Murphy, C. P. Thomas, D. Steinhilber, S. G. Gelhaus, M. H. Gelb, H. Kühn, P.-J. Jakobsson, I. Blair, R. C. Murphy, B. A. Freeman, A. R. Brash, G. A. FitzGerald (2023) Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nat Commun, 14, 7172, doi: 10.1038/s41467-023-41766-w. fulltext
(130) B. Goebel, L. Carpanedo, S. Reif, T. Göbel, N. H. Schebb, D. Steinhilber, A.-K. Häfner (2023) Development of a cell-based model system for the investigation of ferroptosis. Front Cell Death, doi: 10.3389/fceld.2023.1182239 fulltext
(129) E. Koch, A. Löwen, N. Kampschulte, K. Plitzko, M. Wiebel, K.M. Rund, I. Willenberg, N.H. Schebb (2023) Beyond Autoxidation and Lipoxygenases: Fatty Acid Oxidation Products in Plant Oils. J Agric Food Chem, 71, 35, 13092-13106, doi: 10.1021/acs.jafc.3c02724. abstract
(128) E. Villain, A. Chanson, M. Mainka, N. Kampschulte, P. Le Faouder, J. Bertrand-Michel, M. Brandolini-Bulon, B. Charbit, M. Musvosvi, N. Bilek, T.J. Scriba, L. QuintanaMurci, N.H. Schebb, D. Duffy, C. Gladine, the Milieu Interieur Consortium (2023) Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral and T-cell stimulation reveals new immune networks. iSCIENCE, 26, 8, 107422 , doi: 10.1016/j.isci.2023.107422. fulltext
(127) N. Rohwer, J. Jelleschitz, A. Höhn, D. Weber, A.A. Kühl, C. Wang, R.-I. Ohno, N. Kampschulte, A. Pietzner, N.H. Schebb, K.-H. Weylandt, T. Grune (2023) Prevention of colitis-induced liver oxidative stress and inflammation in a transgenic mouse model with increased omega-3 polyunsaturated fatty acids. Redox Biol, 64: 102803, doi: 10.1016/j.redox.2023.102803. fulltext
(126) E. Koch, A. Löwen, S. Nikolay, I. Willenberg, N. H. Schebb (2023) Trans-hydroxy, trans-epoxy and erythro-dihydroxy fatty acids increase during deep-frying. J Agric Food Chem, 71, 19, 7508–7513, doi: 10.1021/acs.jafc.3c00964. abstract
(125) A. Kahnt, N.H. Schebb, D. Steinhilber (2023) Formation of lipoxins and resolvins in human leukocytes. Prostag Oth Lipid M., 166: 106726, doi: 10.1016/j.prostaglandins.2023.106726. fulltext
(124) C. G. Leineweber, M. Rabehl, A. Pietzner, N. Rohwer, M. Rothe, M. Pech, B. Sangro, R. Sharma, C. Verslype, B. Basu, C. Sengel, J. Ricke, N.H. Schebb, K.-H. Weylandt, J. Benckert (2023) Sorafenib increases Cytochrome P450 Lipid Metabolites in Patient with Hepatocellular Carcinoma. Front Pharmacol, 14: 1124214, doi: 10.3389/fphar.2023.1124214. fulltext
(123) F. Richter, M. Friedrich, N. Kampschulte, M. Pohin, G. Alsaleh, I. Guschina, S. Wideman, E. Johnson, M. Borsa, K. Piletic, P. Hahn, H. Schipper, C. Edwards, R. Zechner, N. H. Schebb, F. Powrie, A. K. Simon (2023) Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10. EMBO J, 42: e112202, doi: 10.15252/embj.2022112202, fulltext
(122) K.M. Rund, N.H.Schebb (2023) Quantitative analysis of eicosanoids and other oxylipins –Investigation of oxidative stress and inflammation by means of targeted metabolomics of oxylipins in cell culture. Section in: Ivanisevic, J., Giera, M. (eds) “A Practical Guide to Metabolomics Applications in Health and Disease.” Learning Materials in Biosciences. Springer, Cham. doi: 10.1007/978-3-031-44256-8_13 preprint
(121) N. M. Hartung, M. Mainka, R. Pfaff, M. Kuhn, S. Biernacki, L. Zinnert, N. H. Schebb (2023) Development of a quantitative proteomics approach for cyclooxygenases and lipoxygenases in parallel to quantitative oxylipin analysis allowing the comprehensive investigation of the arachidonic acid cascade. Anal BioanalChem, 415(5), 1-21, doi: 10.1007/s00216-022-04489-3, fulltext
(120) N. H. Schebb, D. Steinhilber (2023) What mediates the inflammation resolution? Function, 2022, 4(1). doi: 10.1093/function/zqac067, fulltext
(119) E.d. Marco, N. Kampschulte, C. Murphey, N.H. Schebb, H. Roche (2023) Oxylipin Status, Before and After LC n-3 PUFA Supplementation, Has Little Relationship with Skeletal Muscle Biology in Older Adults at Risk of Sarcopenia. Prostag Leukotr Ess M 189, 102531. doi: 10.1016/j.plefa.2022.102531, abstract
2022
(118) E. Koch, M. Wiebel, A. Loewen, I. Willenberg, N. H. Schebb (2022) Characterization of the Oxylipin Pattern and Other Fatty Acid Oxidation Products in Freshly Pressed and Stored Plant Oils. J Agric Food Chem, doi: 10.1021/acs.jafc.2c04987, abstract
(117) S. Janciauskiene, S. Tumpara, N. H. Schebb, F. F. R. Buettner, M. Mainka, K. Sivaraman, S. Immenschuh, V. Grau, T. Welte, B. Olejnicka (2022) Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1ß secretion from human PBMCs. Front Pharmacol, doi: 10.3389/fphar.2022.995869, fulltext
(116) E. Koch, M. Bagci, M. Kuhn, N. M. Hartung, M. Mainka, K. M. Rund, N. H. Schebb (2022) GC-MS analysis of oxysterols and their formation in cultivated liver cells (HepG2). Lipids, doi: 10.1002/lipd.12360, pdf
(115) N. Kampschulte, T. Berking, I.E. Çelik, S.F. Kirsch, N. H. Schebb (2022) Inhibition of cytochrome P450 monooxygenase-catalyzed oxylipin formation by flavonoids: Evaluation of structure-activity relationship towards CYP4F2-selective inhibitors. Eur J Med Chem, 238, 114332, doi: 10.1016/j.ejmech.2022.114332 abstract
(114) E. Koch, N. Kampschulte, N.H. Schebb (2022) Comprehensive analysis of fatty acid and oxylipin patterns in n3-PUFA supplements. J Agric Food Chem 70 (13) 3979–3988, doi: 10.1021/acs.jafc.1c07743 abstract
(113) C. Dalle, J. Tournayre , M. Mainka, A. B.-Rasała, M. Pétéra, S. Lefèvre-Arbogast, J. Dalloux-Chioccioli, M. Deschasaux-Tanguy, L Lécuyer , E. Kesse-Guyot, L.Fezeu, S. Hercberg, P.Galan, C. Samieri, K. Zatońska, P.C.Calder, M.F. Hjorth, A. Astrup, A. Mazur, J.Bertrand, N. H. Schebb, A. Szuba, M. Touvier, J. W. Newman, C. Gladine (2022) The Plasma Oxylipin Signature Provides a Deep Phenotyping of Metabolic Syndrome Complementary to the Clinical Criteria. Int. J. Mol. Sci. 23,11688, doi: 10.3390/ijms231911688 pdf
(112) N. H. Schebb, H. Kühn, A. S. Kahnt, K. M. Rund, V. B. O’Donnell, N. Flamand, M. Peters-Golden, P.J. Jakobsson, K. H. Weylandt, N. Rohwer, R. C. Murphy, G. Geisslinger, G. A. FitzGerald, J. Hanson, C. Dahlgren, M. Wessam Alnouri, S.Offermanns, D. Steinhilber (2022) Formation, signaling and occurrence of specialized pro-resolving lipid mediators – what is the evidence so far? Front Pharmacol, 13, 838782, doi 10.3389/fphar.2022 pdf
(111) V. B O’Donnell, G. L. Milne, M. S. Nogueira, M. Giera., N. H. Schebb (2022) Quantitation of oxylipins in biological samples, focusing on plasma and urine. In: Mass Spectrometry for Lipidomics: Methods and Applications, M. Holcapek and K. Ekroos (eds.), Wiley-VCH, 2022. ISBN 978-3-527-35015-5, doi: 10.1002/9783527836512 pdf, ahead of print
(110) M. Mainka, S. George, C. Angioni, R. Ebert, T. Goebel, N. Kampschulte, A. Krommes, D. Thomas, N. H. Schebb, D. Steinhilber, A. S. Kahnt (2022) On the biosynthesis of specialized pro-resolving mediator in human neutrophils and the influence of cell integrity. BBA Lipids, 1867, 159093 doi: 10.1016/j.bbalip.2021.159093 abstract
(109) M. Misheva, K. Kotzamanis, L.C. Davies, V. J. Tyrrell, P. R. S. Rodrigues, G. A. Benavides, C. Hinz, R. C. Murphy, P.Kennedy, P. R. Taylor, M. Rosas, S. A Jones, J. E. McLaren, S. Deshpande, R. Andrews, N. H. Schebb, M. A Czubala1, M. Gurney, M. Aldrovandi, S. W. Meckelmann, P. Ghazal, V. Darley-Usmar, D. White, V. B. O’Donnell (2022) Oxylipin metabolism is controlled by mitochondrial beta-oxidation during bacterial inflammation. Nature Communications 13, 139 doi: 10.1038/s41467-021-27766-8 pdf
2021
(108) E. Marbach-Breitrück, N.Rower, C. Infante-Duarte, S. Romero-Suarez,D. Labuz, H. Machelska, L. Kutzner, N. H. Schebb, M. Rothe P. Reddanna, K. H. Weylandt, L. H. Wieler, D. Heydeck, H. Kuhn (2021) Knock-in mice expressing a 15-lipoxygenating ALOX5 mutant respond differently to experimental inflammation than reported ALOX5-/- mice. Metabolites, doi: 10.3390/metabo11100698. fulltext
(107) R. N. M. Saleh, A. L. West, A. I Ostermann, N. H. Schebb, P. C Calder, A M. Minihane (2021) APOE Genotype Modifies the Plasma Oxylipin Response to Omega-3 Polyunsaturated Fatty Acid Supplementation in Healthy Individuals. Front Nutr, doi: 10.3389/fnut.2021.723813 fulltext
(106) E. Koch, C. Hopmann, L. F. Froehlich, N.H. Schebb (2021) Fatty acid and oxylipin concentration differ markedly between different fetal bovine serums: A cautionary note. Lipids, 56, 613-616. doi: 10.1002/lipd.12321pdf
(105) K. L. Gützkow , J. Ebmeyer, N. Kröncke, N. Kampschulte, L. Böhmert , C. Schöne, N. H.Schebb, R. Benning, A. Bräuning , R. Maul (2021) Metabolic fate and toxicity reduction of aflatoxin B1 after uptake by edible Tenebrio molitor larvae. Food Chem Toxicol, 155, 112375, doi: 10.1016/j.fct.2021.112375 abstract
(104) E. Koch, M. Wiebel, C. Hopmann, N. Kampschulte, N. H. Schebb (2021) Rapid quantification of fatty acids in plant oils and biological samples by LC-MS. Anal BioanalChem, 43 5439-5451, doi: 10.1007/s00216-021-03525-y pdf
(103) C. Schmöcker, H. Gottschall, K. Rund, L. Kutzner, F. Nolte, A. I. Ostermann, D. Hartmann, N. H. Schebb, K. H. Weylandt (2021) Oxylipin patterns in human colon adenomas. Prostag Leukotr Ess, 167, 102269, doi: 10.1016/j.plefa.2021.102269 abstract
(102) N. Rohwer, C.Y.Chiu, C. Smyl, M. Rothe, K. M. Rund, N. H. Schebb, H. Kühn, K.-H. Weylandt (2021) Omega-3 fatty acids protect from colitis via an Alox15-derived eicosanoid. FASEB J, doi: 10.1096/fj.202002340RR pdf
(101) C. Esselun, B. Dilberger; C. V. Silaidos, E. Koch; N. H. Schebb, G. P. Eckert (2021) A Walnut Diet in Combination with Enriched Environment Improves cognitive Function and Affects Lipid Metabolites in Brain and Liver of Aged NMRI Mice. NeuroMolecular Medicine, 23, 140-160, doi: 10.1007/s12017-020-08639-7 pdf
(100) R. G. Snodgrass, Y. Benatzy, D. Namgaladze, M. Mainka, N. H. Schebb, D. Lütjohann, B Brüne (2021) Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation. Cell Death and Differentiation, 28, 1301-1316, doi: 10.1038/s41418-020-00652-4 pdf
2020
(99) L. Kutzner, C. Esselun, N. Franke, K. Schoenfeld, G. P. Eckert, N.H. Schebb (2020) Effect of dietary EPA and DHA on murine blood and liver fatty acid profile and liver oxylipin pattern depending on high and low dietary n6-PUFA. Food Funct, 2020, 11, 9177 - 9191, doi: 10.1039/d0fo01462a pdf
(98) N. M. Hartung, A. I. Ostermann, S. Immenschuh, N. H. Schebb (2020) Combined targeted proteomics and oxylipin metabolomics for monitoring of the COX-2 pathway. Proteomics, doi.10.1002/pmic.201900058, doi: 10.1002/pmic.201900058 pdf
(97) D. Kopczynski, A. Hentschel, C. Coman, N. H. Schebb, T. Hornemann, D. G. Mashek, N. M. Hartung, O. Shevchuk, H.-F. Schött, K. Lorenz, F. Torta, B. Burla, R. Zahedi, A. Sickmann, M. R. Kreutz, C. S. Ejsing, J. Medenbach R. Ahrends (2020) Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. Anal Chem, 90, 13672 - 13676, doi: 10.1021/acs.analchem.0c02793 pdf
(96) M. Mainka, C. Dalle, M. Pétéra, J. Dalloux-Chioccioli, N. Kampschulte, A. I. Ostermann, M. Rothe, J. Bertrand-Michel, J. W. Newman, C. Gladine, N. H. Schebb (2020) Harmonized procedures lead to comparable quantification of total oxylipins across laboratories. J Lipid Research, 2020, 61 (11), 1424 - 1436, doi: 10.1194/jlr.RA120000991 fulltext
(95) L. Kutzner, K. Goloshchapova, M. Jübermann, M. Blum, M. Rothe, S. F. Kirsch, W.-H. Schunck, H.Kühn, Nils Helge Schebb (2020) Human lipoxygenase isoforms form complex patterns of di- and tri-oxygenated compounds from eicosapentaenoic acid. BBA Lipids, 1865 (12), 158806, doi: 10.1016/j.bbalip.2020.158806 abstract
(94) N. Kampschulte, A. Alasmer, M. Empl, M. Krohn, P. Steinberg, N. H. Schebb (2020) Dietary polyphenols inhibit the Cytochrome P450 Monooxygenase branch of the arachidonic acid cascade with remarkable structure-dependent selectivity and potency. Agric Food Chem, 68 (34) 9235-9244, doi: 10.1021/acs.jafc.0c04690 pdf
(93) R. Greite, K. Derlin, B. Hensen, A. Thorenz , S. Rong, R. Chen, M.S. Jang, J. H Bräsen, M. Meier, I. Willenberg, H. Haller, D. Panigrahy, B.D. Hammock, N.H. Schebb, F. Gueler (2020) Early antihypertensive treatment and ischemia-induced acute kidney injury. Am J Physiol-Renal, 319 (4), F563 - F570, doi: 10.1152/ajprenal.00078.2020 abstract
(92) S. Hellhake, S. W. Meckelmann, M. T. Empl, K. Rentmeister, W. Wißdorf, P. Steinberg, O. J. Schmitz, T. Benter, Nils Helge Schebb (2020) Non-targeted and targeted analysis of oxylipins in combination with charge-switch derivatization by ion mobility high-resolution mass spectrometry. Anal BioanalChem 412 (23), 5743-5757, doi: 10.1007/s00216-020-02795-2 pdf
(91) E. Koch, M. Mainka, C. Dalle, A. I. Ostermann, K. M. Rund, L. Kutzner, L.-F. Froehlich, J. Bertrand-Michel, C. Gladine, N.H. Schebb (2020) Stability of oxylipins during plasma generation and long-term storage. Talanta, 217, 121074, doi: 10.1016/j.talanta.2020.121074 abstract
(90) R. Ebert, R. Cumbana, C. Lehmann, L. Kutzner, A. Toewe, N. Ferreirós, M.J. Parnham, N. H. Schebb, D. Steinhilber, A.S. Kahnt (2020) Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived marcophages. BBA Lipids, 1865 (9), 158702, doi: 10.1016/j.bbalip.2020.158702 abstract
(89) S. Vordenbäumen, A. Sokolowski, L. Kutzner, K. M. Rund, C. Düsing, G. Chehab, J. G. Richter, R. Brinks, M. Schneider, N. H. Schebb (2020) Erythrocyte membrane polyunsaturated fatty acid profiles are associated with systemic inflammation and fish consumption in systemic lupus erythematosus: a cross-sectional study. Lupus. 29 (6), 554-559, doi: 10.1177/0961203320912326 abstract
(88) C. G. Leineweber, A. Pietzner, U. B. Blessin, A. Loew, M. Rothe, E. Schott, N. H. Schebb, K. H. Weylandt (2020) Assessment of the Effect of Sorafenib on Omega-6 and Omega-3 Epoxyeicosanoid Formation in Patients with Hepatocellular Carcinoma. Int J of Mol Sci, 21, 1875, doi: 10.3390/ijms21051875 pdf
(87) K. M. Rund, F. Nolte, J. Doricic, R. Greite, R. Lichtinghagen, F. Gueler, N. H. Schebb (2020) Clinical blood sampling for oxylipin analysis – Effect of storage and pneumatic tube transport of blood on free and total oxylipin profile in human plasma and serum. Analyst, 2020, 145, 2378, doi: 10.1039/c9an01880h pdf
(86) N. Rohwer, A. A. Kühl, A. Ostermann, N. H. Schebb, D. Zopf, F. M. McDonald, K-H. Weylandt (2020) Effects of chronic low-dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis. Cancer Medicine 2020, 9; 2535-2550, doi: 10.1002/cam4.2881 pdf
(85) K.M. Rund, S. Peng, R. Greite, C. Claaßen, F. Nolte, J.-M. Galano, L. Balas, T. Durand, R. Chen, F. Guele, N. H Schebb (2020) Dietary omega-3 PUFA improved tubular function after ischemia induced acute kidney injury in mice but did not attenuate impairment of renal function. Prostag Oth Lipid M. 146, 106386, doi: 10.1016/j.prostaglandins.2019.106386 abstract
(84) E. Marbach-Breitrück, L. Kutzner, M. Rothe, R. Gurke, Y. Schreiber, P. Reddanna, N. H. Schebb, S. Stehling, L. Wieler, D. Heydeck, H. Kuhn (2020) Functional characterization of knock-in mice expressing a 12/15-lipoxygenating ALOX5 mutant instead of the 5-lipoxygenating wildetype enzyme. Antioxid Redox Signal, 32, 1-17, doi: 10.1089/ars.2019.7751 abstract
(83) A. I. Ostermann, E. Koch, K. M. Rund, L. Kutzner, M. Mainka, N. H. Schebb (2020) Targeting Esterified Oxylipins by LC-MS – Effect of Sample Preparation on Oxylipin Pattern. Prostag Oth Lipid M. 146, 106384, doi: 10.1016/j.prostaglandins.2019.106384 pdf
2019
(82) T. Greupner, E. Koch, L. Kutzner, A. Hahn, N.H. Schebb, J. P. Schuchardt (2019) Single-dose SDA-rich Echium oil increases plasma EPA, DPAn3 and DHA concentrations. Nutrients, 11, 2346, doi: 10.3390/nu11102346 pdf
(81) P. Waindok, E. Janecek-Erfurth, D. Lindenwald, E. Wilk, K. Schughart, R. Geffers, J.-M. Galano, L. Balas, T. Durand, K.M. Rund, N. H. Schebb, C. Strube (2019) Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and T. cati-induced neurotoxocarosis. PLOS Neglected Tropical Diseases, 13, 1-20, doi: 10.1371/journal.pntd.0007706 pdf
(80) T. Zhou, B. Ringbeck, N. H. Schebb, J. Scherkenbeck (2019) Isolation, Total Synthesis and Quantification of Caffeoylisocitric Acid, a Characteristic Ingredient of the Superfood Amaranth. Tetrahedron, 75 (33), 4479-4485, doi: 10.1016/j.tet.2019.06.033 abstract
(79) N. M. Hartung, J. Fischer, A. I.Ostermann, K. M. Rund, N. H. Schebb, U. Garscha (2019) Impact of food polyphenols on oxylipin biosynthesis in human neutrophils. BBA Lipids, 1864 (10), 1536-1544, doi: 10.1016/j.bbalip.2019.05.002 abstract
(78) C. Gladine, A.I. Ostermann, J.W. Newman, N. H. Schebb (2019) MS-based targeted metabolomics of eicosanoids and other oxylipins: analytical and inter-individual variabilities. Free Radical Biology & Medicine, 144, 72-89, doi: 10.1016/j.freeradbiomed.2019.05.012 abstract
(77) S. Tewes, F. Gueler, M. Gutberlet, N. H. Schebb, K. Rund, J.T. Kielstein, V.D. VoChieu, S. Rauhut, H. Haller, F. Wacker, K. Hueper (2019) Single-dose diclofenac in healthy volunteers can cause decrease in renal perfusion measured by functional magnetic resonance imaging. J. Pharm. Pharmacol. 71(8), 1262-1270, doi: 10.1111/jphp.13105 abstract
(76) K.M. Rund, D. Heylmann, N. Seiwert, S. Wecklein, C. Oger, J.-M. Galano, T. Durand, R. Chen, F. Gueler, J. Fahrer, J. Bornhorst, N. H. Schebb (2019) Formation of trans-epoxy fatty acids correlates with formation of isoprostanes and could serve as biomarker of oxidative stress. Prostag Oth Lipid M. 144, 1-10, doi: 10.1016/j.prostaglandins.2019.04.004 abstract
(75) L. Kutzner, K. M. Rund, A. I. Ostermann, N. M. Hartung, J.-M. Galano, L. Balas, T. Durand, M. S. Balzer, S. David, N. H. Schebb (2019) Development of an optimized LC-MS method for the detection of specialized pro-resolving mediators in biological samples. Front. Pharmacol. 10:169, doi: 10.3389/fphar.2019.00169 pdf
(74) N. M. Hartung, M. Mainka, N. Kampschulte, A. I. Ostermanna, N. H. Schebb (2019) A strategy for validating concentrations of oxylipin standards for external calibration. Prostag Oth Lipid M, 141, 22-24, doi: 10.1016/j.prostaglandins.2019.02.006 abstract
(73) K.H. Weylandt, C. Schmöcker , A. Ostermann, L. Kutzner, I. Willenberg S. Kiesler , E. Steinhagen-Thiessen, N. H. Schebb, U. Kassner (2019) Activation of lipid mediator formation due to lipoprotein apheresis. Nutrients, Nutrients 2019, 11(2), 363, doi: 10.3390/nu11020363 pdf
(72) A. I. Ostermann, A. L. West, K. Schoenfeld, L. M. Browning, C. G. Walker, S. A. Jebb, P. C. Calder, N. H. Schebb (2019) Plasma oxylipins respond in a linear dose-response manner with increased intake of eicosapentaenoic and docosahexaeanoic acids: results from a randomized controlled trial in healthy humans. Am J Clin Nutr 2019;109:1–13, doi: 10.1093/ajcn/nqz016 abstract
(71) L. Paloque, T. Perez-Berezo, A. Abot, J. Dalloux-Chioccioli, S. Bourgeade-Delmas, P. Le Faouder, J. Pujo, M.-A. Teste, J.-M. François, N. H. Schebb, M. Mainka, C. Rolland, C. Blanpied, G. Dietrich, J. Bertrand-Michel, C. Deraison, A. Valentin, N. Cenac (2019) Polyunsaturated fatty acid metabolites: biosynthesis in Leishmania and role in parasite/host interaction. J Lipid Res, 60, 636-647, doi: 10.1194/jlr.M091736 abstract
2018
(70) A. I. Ostermann T. Greupner, L. Kutzner, N. M. Hartung, A. Hahn, J. P. Schuchardt, N. H. Schebb (2018) Intra-individual variance of human plasma oxylipin pattern: Low inter-day variability in fastened blood samples versus high variability during the day. Anal Methods, 10, 4935 – 4944, doi: 10.1039/c8ay01753k pdf
(69) C. Dalle, A. I. Ostermann, T. Konrad, C. Coudy-Gandilhon, A. Decourt, J. C. Barthélémy , F. Roche, L. Féasson, A. Mazur, D. Béchet, N. H. Schebb, C. Gladine (2018) Muscle loss associated changes of oxylipin signatures during biological aging: an exploratory study from the PROOF cohort. J Gerontol A Biol Sci Med Sci; 74(5), 608-615, doi: 10.1093/gerona/gly187 abstract
(68) T. Greupner, L. Kutzner, S. Pagenkopf, H. Kohrs, A. Hahn, N. H. Schebb, J. P. Schuchardt (2018) Effects of a low and a high dietary LA/ALA ratio on long-chain PUFA concentrations in red blood cells. Food Funct, 19, 4742-4752, doi: 10.1039/c8fo00735g pdf
(67) H. Gottschall, C. Schmöcker, D. Hartmann, N. Rohwer, K. Rund, L. Kutzner, F. Nolte, A. I. Ostermann, N. H. Schebb, K. H. Weylandt (2018) Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue. J Lipid Res 59(5), 864-871, doi: 10.1194/jlr.M078725 pdf
(66) T. Greupner, L. Kutzner, F. Nolte, A. Strangmann, H. Kohrs, A. Hahn; N. H. Schebb, J.P. Schuchardt (2018) Effects of a 12-week high-α-linolenic acid intervention on EPA and DHA concentrations in red blood cells and plasma oxylipin pattern in subjects with a low EPA and DHA status. Food Funct 9(3), 1587-1600, doi: 10.1039/c7fo01809f pdf
(65) C. Schmöcker, I. W. Zhang, S. Kiesler, U. Kassner, A. I. Ostermann, E. Steinhagen-Thiessen, N. H. Schebb, K. H. Weylandt (2018) Effect of omega-3 fatty acid supplementation on oxylipins in a routine clinical setting. Int Mol Sci 19(1) 180-185, doi: 10.3390/ijms19010180 abstract
(64) K. M. Rund, A. I. Ostermann, L. Kutzner, J.-M. Galano, C. Oger, C. Vigor; S. Wecklein, N. Seiwert, T. Durand, N. H. Schebb (2018) Development of an LC-(ESI-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3- and n6-PUFAs. Anal Chim Acta, 1037, 63-74, doi: 10.1016/j.aca.2017.11.002 abstract
2017
(63) A. I. Ostermann, P. Waindok, M. J. Schmidt, C. Y. Chiu, C. Smyl, N. Rohwer, K. H. Weylandt, N. H. Schebb (2017) Modulation of the Endogenous Omega-3 Fatty Acid and Oxylipin Profile in vivo – A Comparison of the fat-1 Transgenic Mouse with C57BL/6 Wildtype Mice on an Omega-3 Fatty Acid Enriched Diet. PLOS-1. doi: 10.1371/journal.pone.0184470 pdf
(62) C. Schmöcker, U. Kassner, A. I. Ostermann, S. Kiesler, E. Steinhagen-Thiessen, N. H. Schebb, K. H. Weylandt (2017) Effect of different lipid apheresis methods on plasma polyunsaturated fatty acids. Atherosclerosis-supplements, 30, 193-199, doi: 10.1016/j.atherosclerosissup.2017.05.018 abstract
(61) J. P. Schuchardt, A. I. Ostermann, L. Stork, S. Fritsch, H. Kohrs, T. Greupner, A. Hahn, N. H. Schebb (2017) Effect of DHA supplementation on oxylipin levels in plasma and immune cell stimulated blood. Prostag Leukotr Ess, 121, 76-87, doi: 10.1016/j.plefa.2017.06.007 abstract
(60) A.-C. Becker, I. Willenberg, A. Springer, N. H. Schebb, P. Steinberg, C. Strube (2017) Fatty acid composition of free-living and parasitic stages of the bovine lungworm Dictyocaulus viviparus. Molecular & Biochemical Parasitology, 216, 39-44, doi: 10.1016/j.molbiopara.2017.06.008 abstract
(59) A. I. Ostermann, N. H. Schebb (2017) Effects of Omega-3 Fatty Acid Supplementation on the Pattern of Oxylipins – A short review about the modulation of hydroxy-, dihydroxy-, and epoxy-fatty acids. Food Funct, 8, 2355-2367, doi: 10.1039/c7fo00403f pdf
(58) A. I. Ostermann, M. Reutzel, N. Hartung, N. Franke, L. Kutzner, K. Schoenfeld, K. H. Weylandt, G. P. Eckert , N. H. Schebb (2017) A Diet Rich in Omega-3 Fatty Acids Enhances Expression of Soluble Epoxide Hydrolase in Murine Brain. Prostag Oth Lipid M., 133, 79-87, doi: 10.1016/j.prostaglandins.2017.06.001 abstract
(57) L. Kutzner, K. Goloshchapova, S. Stehling, Dagmar Heydeck, H. Kuhn, N. H. Schebb (2017) Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexanoic acid. BBA Lipids, 7, 666–675, doi: 10.1016/j.bbalip.2017.04.001 abstract
(56) S. W. Meckelmann, S. Hellhake, M. Steuck, M. Krohn, N. H. Schebb (2017) Comparison of derivatization/ionization techniques for liquid chromatography tandem mass spectrometry analysis of oxylipins. Prostag Oth Lipid M 130, 1-8, doi: 10.1016/j.prostaglandins.2017.02.003 abstract
(55) L. Kutzner, A. I. Ostermann, T. Konrad, D. Riegel, J. P. Schuchardt, N. H. Schebb (2017) Lipid class specific quantitative analysis of n3-polyunsaturated fatty acid in food supplements. Agric Food Chem, 65, 139-147, doi: 10.1021/acs.jafc.6b03745 abstract
(54) S. Wang, I. Willenberg, M. Krohn, T. Hecker, S. Meckelmann, C. Li, Y. Pan, N. H. Schebb, P. Steinberg, M. T. Empl (2017) Growth-inhibiting activity of resveratrol imine analogs on tumor cells in vitro. PLOS-1, doi.org/10.1371/journal.pone.017050, doi: 10.1371/journal.pone.0170502 pdf
2016
(53) M. Steuck, S. Hellhake, N. H. Schebb (2016) Food Polyphenol Apigenin Inhibits the Cytochrome P450 Monoxygenase Branch of the Arachidonic Acid Cascade. J Agric Food Chem, 64, 8973-8976, doi: 10.1021/acs.jafc.6b04501 abstract
(52) J. P. Schuchardt, A. I. Ostermann, L. Stork, L. Kutzner, H. Kohrs, T. Greupner, A. Hahn, N. H. Schebb (2016) Effects of docosahexaenoic acid supplementation on PUFA levels in red blood cells and plasma. Prostag Leukotr Ess, 115, 12-23, doi: 10.1016/j.plefa.2016.10.005 abstract
(51) I. Willenberg, S. Rong, N. Shushakova, F. Gueler and N. H. Schebb (2016) Characterization of changes in plasma and tissue oxylipin levels in LPS and CLP induced murine sepsis. Inflamm Res. 65, 133-142, doi: 10.1007/s00011-015-0897-7 abstract
(50) K. Moeller, A. I. Ostermann , K. Rund , S. Thoms , C. Blume , F. Stahl , A. Hahn, N. H. Schebb, J. P. Schuchardt (2016) Influence of weight reduction on blood levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and oxylipins in obese subjects. Prostag Leukotr Ess, 106, 39-49, doi: 10.1016/j.plefa.2015.12.001 abstract
(49) P. Nicken, A. v. Keutz, I. Willenberg, A. Ostermann, N. H. Schebb, O. Kershawb, S. Giovanninib, G. Breves and P. Steinberg (2016) Impact of dextran sulphate sodium-induced colitis on the intestinal transport of the colon carcinogen PhIP. Arch Toxicol.90(5), 1093-1102, doi: 10.1007/s00204-015-1546-1 abstract
2015
(48) I. Willenberg, A. K. Meschede, F. Güler M. S. Jang, N. Shushakova and N. H. Schebb (2015) Food polyphenols fail to cause a biologically relevant reduction of COX-2 activity. PLOS-1, 10.1371/journal.pone.0139147, doi: 10.1371/journal.pone.0139147 pdf
(47) A. Haghikia, S. Jörg, A. Duscha, J. Berg, A. Manzel, A. Waschbisch, A. Hammer, D. Lee, C. May, N. Wilck, A. I. Ostermann, N. H. Schebb , D.A. Akkad, D.A. Grohme, M. Kleinewietfeld, J. Thöne, S. Demir, D. N. Müller , R. Gold, R. A. Linker (2015) Dietary fatty acids directly impact CNS autoimmunity via the small intestine. Immunity, 43 (4), 817-829, doi: 10.1016/j.immuni.2015.09.007 abstract
(46) I. Willenberg, M. Michael, J. Wonik and N. H. Schebb (2015) Investigation of the effects of soluble fibers on the absorption of resveratrol and of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) in the Caco-2 cellular model of intestinal absorption. Int J Food Sci Nutr, 66, 677-679, doi: 10.3109/09637486.2015.1077789 abstract
(45) A. I. Ostermann, J. Herbers, I. Willenberg, R. Chen, S. H. Hwang, R. Greite, C. Morisseau, F. Gueler, B. D. Hammock and N. H. Schebb (2015) Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostag Oth Lipid M, 121A, 131-137, doi: 10.1016/j.prostaglandins.2015.06.005 abstract
(44) I. Willenberg, A. I. Ostermann, O. Kershawb, S. Giovanninib, A. v. Keutz, P. Steinberg and N. H. Schebb (2015) Effect of acute and chronic DSS induced colitis on plasma eicosanoid and oxylipin levels in the rat. Prostag Oth Lipid M, 120, 155-160, doi: 10.1016/j.prostaglandins.2015.04.002 abstract
(43) I. Willenberg, A. K. Meschede and N. H. Schebb (2015) Determining COX-2 activity in three different test systems utilizing online-solid phase extraction-liquid chromatography-mass spectrometry for parallel quantification of prostaglandin E2, D2 and thromboxane B2. J Chromatogr A 1391, 40-48, doi: 10.1016/j.chroma.2015.02.059 abstract
(42) P. Nicken, A. v. Keutz, I. Willenberg, L. v. Elsner, G. Hamscher, L. Vanhaecke, B. Schröder, G. Breves, N. H. Schebb and P. Steinberg (2015) Intestinal absorption and cell transforming potential of PhIP-M1, a bacterial metabolite of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Toxicology Letters, 234, 92-98, doi: 10.1016/j.toxlet.2015.02.015 abstract
(41) I. Willenberg, A. I. Ostermann and N. H. Schebb (2015) Targeted metabolomics of the arachidonic acid cascade – Current state and challenges of LC-MS analysis of oxylipins. Anal BioanalChem, 407, 2675–2683, doi: 10.1007/s00216-014-8369-4 abstract
(40) I. Willenberg, L. v. Elsner, P. Steinberg and N. H. Schebb (2015) Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system. Food Chem. 166, 537–543, doi: 10.1016/j.foodchem.2014.06.038 abstract
(39) A. I. Ostermann, I. Willenberg and N. H. Schebb (2015) Comparison of sample preparation methods for the quantitative analysis of eicosanoids and other oxylipins in plasma by means of LC-MS/MS. Anal BioanalChem, 407(5),1403-1414, doi: 10.1007/s00216-014-8377-4 abstract preprint, pdf
(38) I. Willenberg, M. Michael, J. Wonik, L. C. Bartel, M. T. Empl and N. H. Schebb (2015) Investigation of the absorption of resveratrol oligomers in the Caco-2 cellular model of intestinal absorption. Food Chem. 167, 245–250, doi: 10.1016/j.foodchem.2014.06.103 abstract
(37) A. I. Ostermann, I. Willenberg, K. W. Weylandt and N. H. Schebb (2015) Development of an online-SPE-LC-MS/MS method for 26 hydroxylated polyunsaturated fatty acids as rapid targeted metabolomics approach for the LOX, CYP and autoxidation pathways of the arachidonic acid cascade. Chromatographia, 78(5), 415-428, doi: 10.1007/s10337-014-2768-8 abstract
(36) M. T. Empl, P. Kammeyer, R. Ulrich, J. F. Joseph, M. K. Parr, I. Willenberg, N. H. Schebb, W. Baumgärtner, E. Röhrdanz, C. Steffen and P. Steinberg (2015) The influence of chronic L-carnitine on the formation of preneoplastic and atherosclerotic lesions in the colon and aorta of male F-344 rats. Arch Toxicol. 89, 2079-2087, doi: 10.1007/s00204-014-1341-4 abstract
(35) R. Maul, B. Warth, N.H. Schebb, R. Krska, M. Koch and M. Sulyok (2015) In vitro glucuronidation kinetics of deoxynivalenol by human and animal microsomes and recombinant human UGT enzymes. Arch Toxicol. 89, 949-960, doi: 10.1007/s00204-014-1286-7 abstract
2014
(34) A. I. Ostermann, M. Müller, I. Willenberg and N. H. Schebb (2014) Determining the fatty acid composition in plasma and tissues as fatty acid methyl esters by gas chromatography – A comparison of different derivatization and extraction procedures. Prostag Leukotr Ess. 91, 235-241, doi: 10.1016/j.plefa.2014.10.002 abstract preprint, pdf
(33) N. H. Schebb, A. I. Ostermann, J. Yang, B. D. Hammock, A. Hahn and J. P. Schuchardt (2014) Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostag Oth Lipid M, 113-115, 21-29, doi: 10.1016/j.prostaglandins.2014.05.002 abstract
(32) J. P. Schuchardt, I. Schneider, I. Willenberg, J. Yang, B. D. Hammock, A. Hahn and N. H. Schebb (2014) Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA. Prostag Oth Lipid M. 109-111, 23-31, doi: 10.1016/j.prostaglandins.2014.03.001 abstract
(31) N. H. Schebb, J. B. Muvvala, D. Morin, A. R. Buckpitt, B. D. Hammock and R. H. Rice (2014) Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts. Drug Metab Dispos. 42 (7),1098-1102, doi: 10.1124/dmd.114.058206 abstract
(30) J. P. Schuchardt, S. Schmidt, G. Kressel, H. Dong, I. Willenberg, B. D. Hammock, A. Hahn and N. H. Schebb (2014) Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostag Leukotr Ess. 90, 27-37, doi: 10.1016/j.plefa.2013.12.008 abstract
2013
(29) S. Stolte, S. Steudte, I. Willenberg, N. H. Schebb and P. Stepnowski (2013) Ecotoxicity of artificial sweeteners and stevioside. Environ Int. 60, 123-127, doi: 10.1016/j.envint.2013.08.010 abstract
(28) J. P. Schuchardt, S. Schmidt, G. Kressel, H. Dong, I. Willenberg, B. D. Hammock, A. Hahn and N. H. Schebb (2013) Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostag Leukotr Ess. 89, 19-29, doi: 10.1016/j.plefa.2013.04.001 abstract
(27) D. Falck, N. H. Schebb, S. Prihatiningtyas, J. Zhang, F. Heus, C. Morisseau, J. Kool, B. D. Hammock and W. M. A. Niessen (2013) Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures. Chromatographia. 76, 13-21, doi: 10.1007/s10337-012-2343-0 abstract
2012
(26) R. Maul, B. Warth, J. S. Kant, N. H. Schebb, R. Krska, M. Koch and M. Sulyok (2012) Investigation of the hepatic glucuronidation pattern of the Fusarium mycotoxin deoxynivalenol in various species. Chem ResTox. 25, 2715-2717, doi: 10.1021/tx300348x abstract
(25) G. Cherednichenko, R. Zhang, R. A. Bannister, V. Timofeyev, N. Li, E. B. Holland-Fritsch, W. Feng, G. C. Barrientos, N. H. Schebb, B. D. Hammock, K. G. Beam, N. Chiamvimonvat and I. N. Pessah (2012) Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 109 (35), 14158-14163, doi: 10.1073/pnas.1211314109 pdf
(24) I. Willenberg, W. Brauer, M. T. Empl and N. H. Schebb (2012) Development of a rapid LC-UV Method for the Investigation of chemical and metabolic Stability of Resveratrol Oligomers. J Agric Food Chem. 60 (32), 7844-7850, doi: 10.1021/jf302136t abstract
(23) B. Inceoglu, K. M. Wagner, J. Yang, A. Bettaieb, N. H. Schebb, S. H. Hwang, C. Morisseau, F. Haj and B. D. Hammock (2012) Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proc Natl Acad Sci U S A. 109 (28), 11390-11395, doi: 10.1073/pnas.1208708109 pdf
(22) N. H. Schebb, B. Buchholz, B. D. Hammock and R. H. Rice (2012) Metabolism of the Antibacterial Triclocarban by Human Epidermal Keratinocytes to Yield Protein Adducts? J Biochem Mol Toxic. 26 (6), 230-234, doi: 10.1002/jbt.21411 abstract
(21) A. Eißing, D. Fischer, A. Baumann, N. H. Schebb, U. Karst, K. Rose, S. Klumpp and J. Krieglstein (2012) Acetylcholine content and viability of cholinergic neurons are influenced by the activity of protein histidine phosphatase. BMC Neuroscience 13:31, doi: 10.1186/1471-2202-13-31 pdf
(20) C. Morisseau, N. H. Schebb, H. Dong, A. Ulu, P. A. Aronov and B. D. Hammock (2012) Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochem Bioph Res Co. 419 (4), 796-800, doi: 10.1016/j.bbrc.2012.02.108 pdf
(19) N. H. Schebb, K. C. Ahn, H. Dong, S. J. Gee and B. D. Hammock (2012) Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels. Chemosphere. 87 (7), 825-827, doi: 10.1016/j.chemosphere.2011.12.077 pdf
(18) K. C. Ahn, T. Kasagami, H. J. Tsai, N. H. Schebb, T. Ogunyoku, S. J. Gee, T. M. Young and B. D. Hammock (2012) An Immunoassay to Evaluate Human/Environmental Exposure to the Antimicrobial Triclocarban. Environ Sci Techno. 46 (1), 374-381, doi: 10.1021/es202494d pdf
(17) N. H. Schebb, B. Franze, R. Maul, A. Ranganathan and B. D. Hammock (2012) In vitro glucuronidation of the antibacterial triclocarban and its oxidative metabolites. Drug Metab Dispos. 40 (1), 25-31, doi: 10.1124/dmd.111.042283 abstract
2011
(16) N. H. Schebb, I. Flores, T. Kurobe, B. Franze, A. Ranganathan, B. D. Hammock and S. Teh (2011) Bioconcentration, Metabolism and Excretion of Triclocarban in Larval Qurt Medaka (Oryzias latipes). Aquat Toxicol. 105, 448-454, doi: 10.1016/J.aquatox.2011.07.020 pdf
(15) N. H. Schebb, M. Huby, S. H. Hwang, C. Morisseau, and B. D. Hammock (2011) Development of an Online-SPE-LC-MS Based Assay using Endogenous Substrate for Investigation of Soluble Epoxide Hydrolase (sEH) Inhibitors. Anal BioanalChem. 400 (5), 1359-1366, doi: 10.1007/s00216-011-4861-2 pdf
(14) B. Inceoglu, K. Wagner, N. H. Schebb, C. Morisseau, S. L. Jinks, C. Hegedus, A. Ulu, R. Brosnan, A. L. Morrow and B. D. Hammock (2011) Epoxy-fatty acid produced antinociception is driven by pain and elevated cAMP. Proc Natl Acad Sci U S A. 108, (12), 5093-5097, doi: 10.1073/pnas.1101073108 pdf
(13) N. H. Schebb, B. Inceoglu, K. C. Ahn, C. Morisseau, S. Gee and B. D. Hammock (2011) Investigation of human exposure to triclocarban after showering, and preliminary evaluation of its biological effects. Environ Sci Techno. 45 (7), 3109-3115, doi: 10.1021/es103650m pdf
(12) N. H. Schebb, B. Inceoglu, K. Wagner, T. Rose and B. D. Hammock (2011) Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies. Anal Methods. 3, 420-428, doi: 10.1039/c0ay00714e pdf
2010
(11) A. Baumann, W. Lohmann, T. Rose, K. C. Ahn, B. D. Hammock, U. Karst and N. H. Schebb (2010) Electrochemistry-mass spectrometry unveils the formation of reactive triclocarban (TCC) metabolites. Drug Metab Dispos. 38, 2130-2138, doi: 10.1124/dmd.110.034546 pdf
(10) M. Siemerink, N. H. Schebb, A. Liesener, M. Vogel, H. Hayen and U. Karst (2010) Development of a fast LCMS-based Screening-Method for Angiotensin-Converting-Enzyme (ACE)-Inhibitors in complex natural mixtures like snake venom. Rapid Commun Mass Spectrom. 24, 687-697, doi: 10.1002/rcm.4428 abstract
(9) A. Braune, S. E. Kulling, R. Maul, N. H. Schebb and M. Blaut (2010) The red clover isoflavone irilone is largely resistant to degradation by the human gut microbiota. Mol Nutr Food Res. 54, 929-938, doi: 10.1002/mnfr.200900233 abstract
2009
(8) N. H. Schebb, D. Falck, E-M. Hein, U. Karst and H. Hayen (2009) A fast LC-ESI-MS Method for Monitoring Phospholipase A2 Activity. J Chromatogr A. 1216, 5249-5255, doi: 10.1016/j.chroma.2009.05.020 abstract
(7) N. H. Schebb, T. Vielhaber, A. Jousset and U. Karst (2009) Development of a Liquid Chromatography-Based Screening Methodology for Proteolytic Enzyme Activtiy. J Chromatogr A. 1216, 4407-4415, doi: 10.1016/j.chroma.2009.03.053 abstract
(6) N. H. Schebb, H. Faber, R. Maul, F. Heus, J. Kool, H. Irth and U. Karst (2009) Analysis of Glutathione Adducts of Patulin by Means of Liquid Chromatography (HPLC) with Biochemical Detection (BCD) and Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS). Anal Bioanal Chem. 394, 1361-1373, doi: 10.1007/s00216-009-2765-1 abstract
2008
(5) N. H. Schebb, F. Heus, T. Saenger, H. Irth, U. Karst and J. Kool (2008) Development of a Countergradient Parking System for Gradient Liquid Chromatography with Online Biochemical Detection of Serine Protease Inhibitors. Anal Chem. 80 (17), 6764-6772, doi: 10.1021/ac801035e abstract
(4) N. H. Schebb, D. Fischer, E-M. Hein, H. Hayen, J. Krieglstein, S. Klumpp and U. Karst (2008) Fast sample preparation and liquid chromatography-tandem mass spectrometry method for assaying cell lysate acetylcholine. J Chromatogr A. 1183, 100-107, doi: 10.1016/j.chroma.2008.01.033 abstract
(3) R. Maul, N. H. Schebb and S. E. Kulling (2008) Application of LC and GC hyphenated with mass spectrometry as tool for characterization of unknown derivatives of isoflavonoids. Anal BioanalChem. 391, 239-250, doi: 10.1007/s00216-008-1884-4 abstract
2007
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(1) A. Liesener, A. M. Perchuc, R. Schöni, N. H. Schebb, M. Wilmer and U. Karst (2007) Screening of acetylcholinesterase inhibitors in snake venom by electrospray mass spectrometry. Pure Appl Chem. 79 (12), 2339-2349, doi: 10.1351/pac200779122339 pdf
