Dr. Vivien Michaelis
Young investigator (Food Chemistry with focus on Toxicology)
Faculty of Mathematics and Natural Sciences, University of Wuppertal
Gaußstraße 20
42119 Wuppertal
eMail: michaelis[a]uni-wuppertal.de
Research interests
The main research interest involves the impact of essential food constituents and food contaminants in the background of pregnancy, with the focus on the toxic trace element mercury and essential trace elements. Particularly highlighted will be investigations on adverse outcomes of metal overexposure on cellular structures of the placenta, taking environmental and nutritional exposure into account.
Qualifications and Scientific Career
| 01/2023 – now | University of Wuppertal, Germany; Position: “Habillitandin” (Young Investigator), Food Chemistry with Focus on Toxicology, University of Wuppertal, Germany |
| 05/2019 – 10/2022 | PhD thesis in the research group of Prof. Dr. Julia Bornhorst, Food Chemistry with Focus on Toxicology, University of Wuppertal, Germany |
| 04/2019 | 1st state examination/ Master’s Degree in Food Chemistry, University of Wuppertal, Germany |
| 10/2018 – 04/2019 | Research thesis in the research group of Tanja Schwerdtle, Institute of Nutritional Sciences, University of Potsdam, Germany |
| 10/2013 – 04/2019 | Studies of Food Chemistry, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Germany |
Membership in Scientific Committees
| Since 2024 | Member of the Society of Toxicology within the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) |
| Since 2023 | Member of the European Placenta Group (EPG) |
| Since 2020 | Member of the International Federation of Placenta Associations (IFPA) |
| Since 2019 | Member of the European Environmental Mutagenesis & Genomic Society (EEMGS) |
| Since 2019 | Member of the German Environmental Mutagenesis and Genomics Society (GUM) |
| Since 2019 | Member of the Society for Minerals and Trace Elements (GMS) |
| Since 2019 | Member of the Society of Food Chemistry (LChG/GDCh) |
Important awards
| 07/2024 | Josef-Schormüller Scholarship of the German Society for Food Chemistry for a research stay abroad |
| 03/2024 | Lab exchange scholarship of the German Society for Minerals and Trace Elements (GMS) |
| 08/2023 | Future Award of the German Society for Food Chemistry for the best dissertation in the subject Food Chemistry |
Publications
2024
V. Michaelis*, L. Klemens, A. Thiel. A. Gremme, M. Schwarz, A. P. Kipp, H. Zischka, „Revealing species-specific mercury transfer and toxicity mechanisms in placental trophoblasts“, Chemosphere, 2024, DOI: 10.1016/j.chemosphere.2024.143870.
A. Thiel; F. Drews; Pirritano, M. Pirritano; Schumacher, F. Schumacher; V. Michaelis; M. Schwarz; S. Franzenburg; T. Schwerdtle; B. Michalke; A.P. Kipp; et al. „Transcriptomics pave the way into mechanisms of cobalt and nickel toxicity: Nrf2-mediated cellular responses in liver carcinoma cells.” Redox Biology, 2024, DOI: 10.1016/j.redox.2024.103290.
A. Thiel, V. Michaelis, M. Restle, S. Figge, M. Simon, T. Schwerdtle, J. Bornhorst, „Single is not combined: The role of Co and Ni bioavailability on toxicity mechanisms in liver and brain cells “, Chemosphere, 2024, DOI: 10.1016/j.chemosphere.2024.142091
H. K. J. Friedrich, B. Michalke, U. Karst. V. Michaelis*, “Using L-cysteine to enhance calibration range and prevent a memory effect in mercury analysis of complex samples via ICP-OES”, Journal of Trace Elements in Medicine and Biology, 2024, DOI: 10.1016/j.jtemb.2024.127467
O. M. Ijomone, A-K. Weishaupt, V. Michaelis, O. K. Ijomone, J. Bornhorst, „p38- and ERK-MAPK Signalling Modulate Developmental Neurotoxicity of Nickel and Vanadium in the Caenorhabditis elegans Model”, Kinases and Phosphatases, 2024, DOI: 10.3390/kinasesphosphatases2010003
2023
V. Michaelis, S. Kasper, L. Naperkowski, J. Pusse, A. Thiel, F. Ebert, M. Aschner, T. Schwerdtle, H. Haase, J. Bornhorst, “The impact of zinc on manganese bioavailability and cytotoxicity in HepG2 Cells”, Molecular Nutrition and Food Research, 2023, DOI: 10.1002/mnfr.202200283
2022
V. Michaelis, L. Aengenheister, M. Tuchtenhagen, J. Rinklebe, F. Ebert, T. Schwerdtle, T. Buerki-Thurnherr, J. Bornhorst, „Differences and Interactions in Placental Manganese and Iron Transfer across an In Vitro Model of Human Villous Trophoblasts”, International Journal of Molecular Sciences – Special Issue: “Homeostasis: Metals and Cellular Redox and Immunity Status”, 2022, DOI: 10.3390/ijms23063296
M.M. Nicolai, B. Witt, S. Friese, V. Michaelis, L. Hölzl-Armstrong, M. Martin, F. Ebert, T. Schwerdtle, J. Bornhorst, „Mechanistic studies on the adverse effect of manganese exposure in differentiated LUHMES cells”, Food and Chemical Toxicology, 2022, DOI: 10.1016/j.fct.2022.112822
2021
J. Baesler, V. Michaelis, M. Stiboller, H. Haase, M. Aschner, T. Schwerdtle, S.R. Sturzenbaum, J. Bornhorst, „Nutritive Manganese and Zinc Overdosing in Aging C. elegans Results in a Metallothionein-Mediated Alteration in Metal Homeostasis”, Molecular Nutrition and Food Research, 2021, DOI: 10.1002/mnfr.202001176
